A report by Caballero and colleagues in JAMA published July 25, 2023 reviewed research on acute bacterial sinusitis in children. This blog is based partially on that article.
Most upper respiratory infections in children are due to a virus and go away without an antibiotic. Symptomatic treatment is all that is needed. Only about “7.5% of upper respiratory infections are complicated by acute bacterial sinusitis.”
Bacterial sinusitis is suspected based on the “duration and severity of the symptoms.” So, it is mainly a clinical decision and normally does not involve testing.
For years it was thought that bacterial sinusitis should be considered if a nasal discharge is colored yellow or brown rather than clear. Recent research shows that the color does not predict a response to antibiotics.
Interestingly, research has also shown that “most cases of acute bacterial sinusitis do not require an antibiotic.” Typically, even bacterial infections show limited benefit from taking an antibiotic. They usually reduce the duration of the infection only by two days (7 days rather than 10). Symptoms also show only modest improvement with antibiotics.
It is also important to recognize potential side-effects from the use of antibiotics. There is a “two-fold risk of diarrhea.” Allergic reactions may occur, and the risk of bacterial resistance to the antibiotic will reduce its efficacy during future use. Given the minimal benefit from antibiotics, the added cost is another reason to limit its use except in more serious cases.
Finally, it is worth knowing that obtaining bacterial cultures is often not helpful. That is because the bacteria that can cause sinus infections are often found in the nose when there is no infection. This is called “colonization.” Also, the test can pick up “antigenic or genetic material” from a bacteria that was causing an infection but has cleared up.
The bottom line is that acute sinusitis in children is due to a virus most of the time. Antibiotics are not helpful. Only symptomatic treatment is indicated.
Even when the infection is due to a bacteria, antibiotics are usually not needed and should be reserved only for more serious infections.
Peter M. Hartmann, MD
Family Medicine & Psychiatry